Las Vegas has always been the city that never sleeps, and the Strip proves it every night with bright lights, flowing crowds, and endless entertainment. For visitors and locals alike, the question often comes up: are any dispensaries actually open 24 hours on the Las Vegas Strip? After all, nightlife and cannabis culture go hand in hand, and timing matters when you want to enjoy both.
The good news is yes—you can absolutely find dispensaries open around the clock in Vegas. While not every shop operates on a 24/7 schedule, a handful of trusted names have built their reputations on never closing their doors.
Planet 13 is the crown jewel of late-night cannabis shopping. Known as the world’s largest dispensary, this massive superstore near the Strip is more than just a retail shop—it’s an attraction in its own right. Visitors can browse hundreds of products, watch the interactive art displays, and even grab a bite from the on-site café. Open 24/7, Planet 13 has become the ultimate destination for tourists who want the full Vegas cannabis experience at any hour of the day.
Another strong option is Thrive Cannabis Marketplace’s Strip location on Sammy Davis Jr Drive, near Resorts World. Thrive emphasizes convenience and variety, making it a solid choice for people heading to or from the Strip late at night. Its 24-hour operations mean customers can swing by after a show, before heading out to a nightclub, or even on the way back to their hotel in the early morning hours.
A few minutes off the Strip, NuLeaf provides another dependable option. Located on East Twain Avenue, it’s a smaller footprint than Planet 13, but its reputation for fast service and a wide range of products makes it a favorite. Open 24 hours in-store and offering all-day pick-up, NuLeaf ensures customers never have to watch the clock.
SLV Cannabis Dispensary, while a little farther out on Boulder Highway, rounds out the list of around-the-clock shops. It may not have the glitz of Planet 13 or Thrive, but it delivers what matters most—availability and selection—especially for locals and seasoned visitors who know where to look.
Locals also note a few other reliable names—such as Reef, Jade, and NV Made—that frequently run 24/7 schedules. While hours can occasionally shift, these dispensaries are often trusted stops for night owls.
Quick Summary:
- Planet 13 – Near the Strip, massive superstore, open 24/7.
- Thrive (Strip location) – 2975 S Sammy Davis Jr Dr, open 24/7.
- NuLeaf – 430 E Twain Ave, minutes off the Strip, in-store and pick-up 24/7.
- SLV Cannabis – Boulder Highway, open 24/7.
- Reef, Jade, NV Made – Other local favorites often operating around the clock.
Final Thoughts
Las Vegas may no longer run entirely on a 24-hour clock like in decades past, but cannabis remains one of the industries keeping the tradition alive. Whether you’re looking for a late-night edible, a pre-roll before heading to Fremont Street, or simply want to explore the biggest dispensary in the world, Vegas has options that never close. For visitors, it’s another reminder that this city is truly built on convenience, fun, and unforgettable experiences—any time of day or night.